Effect of Midodrine in Patients with Liver Cirrhosis and Refractory Ascites
نویسندگان
چکیده
منابع مشابه
Midodrine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study.
BACKGROUND & AIMS Splanchnic arterial vasodilatation plays an important role in cirrhotic ascites. The aim of this study was to evaluate the effects of long term administration of midodrine on systemic hemodynamics, renal function, and control of ascites in patients with cirrhosis and refractory or recurrent ascites. METHODS Forty cirrhotic patients with refractory or recurrent ascites were p...
متن کاملBeneficial effect of midodrine in hypotensive cirrhotic patients with refractory ascites.
Ascites is the most frequent complication of cirrhosis, occurring in nearly 50% of patients within 10 years after cirrhosis is diagnosed.1 A proportion of these patients require large-volume paracentesis (LVP) for symptom relief when other treatment modalities are unsuccessful or impossible. However, frequent LVP is associated with patient discomfort, decreased quality of life, and increased po...
متن کاملAscites, refractory ascites and hyponatremia in cirrhosis
Ascites is the most common complication related to cirrhosis and is associated with increased morbidity and mortality. Ascites is a consequence of the loss of compensatory mechanisms to maintain the overall effective arterial blood volume due to worsening splanchnic arterial vasodilation as a result of clinically significant portal hypertension. In order to maintain effective arterial blood vol...
متن کاملTreatment of refractory ascites with an automated low‐flow ascites pump in patients with cirrhosis
BACKGROUND Refractory ascites (RA) is a frequent complication of cirrhosis, requiring large volume paracentesis or placement of a transjugular intrahepatic portosystemic shunt (TIPSS). The automated low-flow ascites pump (alfapump, Sequana Medical AG, Zurich, Switzerland) is an innovative treatment option for patients with RA. AIM To assess safety and efficacy of this treatment in patients wi...
متن کاملComparison of the effect of midodrine versus octreotide on hemodynamic status in cirrhotic patients with ascites
BACKGROUND In cirrhotic patients peripheral vasodilatation may decrease renal blood flow and subsequently raises plasma renin activity. Octreotide with several mechanisms causes peripheral arterial vasoconstriction. Midodrine is an alpha agonist and acts as a peripheral vasoconstrictor; therefore it may reduce plasma renin activity and improve renal function. In this study the effects of these ...
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ژورنال
عنوان ژورنال: American Journal of Internal Medicine
سال: 2017
ISSN: 2330-4316
DOI: 10.11648/j.ajim.20170501.13